Missouri Career Center Sikeston
Career Center — Sikeston, MO
Updated July 2026
Wide range of services to those seeking employment, retraining, Trade Act, NAFTA, Work-force Investment Programs, and job search to include Missouri WORKS! For information on unemployment insurance, contact 800-320-2519. A veterans representative is available at this location.
Address & Contact
202 South Kingshighway
Sikeston, MO 63801
Fax: 573-472-4577
8:00am - 4:30pm, Mon, Tues, Wed & Fri; 9am-4:30 Thursday
Services
- UI Filing Assistance by Phone
- UI Filing Assistance Online
- UI Filing Assistance from Staff
- File Unemployment Insurance Claim
Helpful Guides
What to Do After Losing Your Job: A Step-by-Step Checklist
The first two weeks after a layoff matter most. Here is the order to tackle unemployment benefits, health insurance, and your budget.
Learn more →Unemployment Eligibility Requirements: Who Qualifies
The three tests every state uses to decide unemployment eligibility, and the separation reasons that typically help or hurt your claim.
Learn more →